A new cytotoxic pregnanone from Calotropis gigantea.

نویسندگان

  • Zhu-Nian Wang
  • Mao-Yuan Wang
  • Wen-Li Mei
  • Zhuang Han
  • Hao-Fu Dai
چکیده

A new pregnanone, named calotropone (1), was isolated from the EtOH extract of the roots of Calotropis gigantea L. together with a known cardiac glycoside. The structures were elucidated by a study of their physical and spectral data. Compounds 1 and 2 displayed inhibitory effects towards chronic myelogenous leukemia K562 and human gastric cancer SGC-7901 cell lines.

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عنوان ژورنال:
  • Molecules

دوره 13 12  شماره 

صفحات  -

تاریخ انتشار 2008