Recurrent Burkholderia infection in patients with chronic granulomatous disease: 11-year experience at a large referral center.

نویسندگان

  • David E Greenberg
  • Joanna B Goldberg
  • Frida Stock
  • Patrick R Murray
  • Steven M Holland
  • John J Lipuma
چکیده

The epidemiology of Burkholderia infection in persons with chronic granulomatous disease is poorly understood. We used species-specific polymerase chain reaction-based assays and genotyping analyses to identify 32 strains representing 9 Burkholderia species among 50 isolates recovered from 18 patients with chronic granulomatous disease. We found that recurrent pulmonary infection with distinct Burkholderia strains is common in chronic granulomatous disease.

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عنوان ژورنال:
  • Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

دوره 48 11  شماره 

صفحات  -

تاریخ انتشار 2009