Science Imitates Art The Cloning of Mice from Olfactory Sensory Neurons

نویسنده

  • John Ngai
چکیده

The functional identity of an olfactory sensory neuron is defined by its expression of one odorant receptor from a large multigene family. The complexity of this process has led to speculation that DNA rearrangements are used to limit the expression of one receptor gene per cell. However, a recent report in Nature directly rules out irreversible DNA rearrangements as a mechanism for odorant receptor gene choice.

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عنوان ژورنال:
  • Cell

دوره 116  شماره 

صفحات  -

تاریخ انتشار 2004