Medial frontal ~ 4 Hz activity in humans and rodents is attenuated in PD patients and in 1 rodents with cortical dopamine depletion
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چکیده
Medial frontal ~4 Hz activity in humans and rodents is attenuated in PD patients and in 1 rodents with cortical dopamine depletion 2 3 Krystal L. Parker, Kuan-Hua Chen, Johnathan R. Kingyon, James F. Cavanagh, Nandakumar S. 4 Narayanan 5 1Department of Neurology, 2Aging Mind and Brain Initiative, Carver College of Medicine, University 6 of Iowa, Iowa City, IA, and 3Department of Psychology, University of New Mexico 7 8 Running title: MFC ~4 Hz rhythms and PD 9
منابع مشابه
Medial frontal ∼4-Hz activity in humans and rodents is attenuated in PD patients and in rodents with cortical dopamine depletion.
The temporal control of action is a highly conserved and critical mammalian behavior. Here, we investigate the neuronal basis of this process using an interval timing task. In rats and humans, instructional timing cues triggered spectral power across delta and theta bands (2-6 Hz) from the medial frontal cortex (MFC). Humans and rodents with dysfunctional dopamine have impaired interval timing,...
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