Synthesis and spectral study of a novel distamycin conjugate

نویسندگان

  • M. J. Pineda
  • P. G. Baraldi
  • R. Romagnoli
  • M. A. Gallo
  • A. Espinosa
چکیده

The 1H and 13C NMR resonances for a novel distamycin conjugate, 3-[1-methyl-4-[1-methyl-4-[1-methyl-4-[N1 -[5methyl-2,4(1H,3H)pyrimidinedione]acetylamino]pyrrole-2-carboxamido]pyrrole-2-carboxamido]pyrrole-2carboxamido]propionamidine hydrochloride (1), were assigned, using the concerted application of oneand two-dimensional NMR techniques including nuclear Overhauser effect difference, DEPT, HMQC and HMBC experiments. Copyright  2003 John Wiley & Sons, Ltd.

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تاریخ انتشار 2003