17-P009 Tsukushi is a Frizzled ligand that, in competition with Wnt2b, regulates the proliferation of retinal stem/progenitor cells
نویسندگان
چکیده
Oct-4, Nanog, Nodal, Sox2, E-cadherin, and FoxD3. In addition, the cells were induced to differentiate into three somatic germ layers, germ cell progenitors and into extraembryonic lineages. This is the first demonstration that pEpiSC can be expanded invitro and that they share similar signalling mechanisms to human ESC and mouse epiblast stem cells. pEpiSC represent a valuable tool for modelling multiple human diseases.
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ورودعنوان ژورنال:
- Mechanisms of Development
دوره 126 شماره
صفحات -
تاریخ انتشار 2009