Embryonic Sex Differentiation and Sex Hormones (1947), by Carl R. Moore

In 1947, Carl Richard Moore, a researcher at the University of Chicago [6], in Chicago, Illinois, wrote Embryonic Sex Differentiation and Sex Hormones, which was published in the same year as a first-edition monograph. In the book, Moore argues that regulation [7] of sex differentiation [8] in mammals is not controlled by sex hormones [9] secreted by embryonic sex organs (gonads), but is controlled by non-hormonal genetic factors. In support of his hypothesis, Moore describes the current literature on sex differentiation [8], and he reviews experiments on vertebrates and invertebrates and his own work with opossum [10] (Didelphis virginiana [11]) young.