Use of ibuprofen in children, focusing on comparative analgesic and antipyretic efficacy and safety

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Antipyretic efficacy of acetaminophen and ibuprofen in children aged 6 months to 10 years

Introduction: Fever and consequent convulsion are among major concerns for parents of febrile children. Many antipyretic drugs are applied excessively to decrease fever in children. This research is designed to study the efficacy and stability effects of cetaminophen and Ibuprofen in febrile children aged 6 months to 10 years old. Methods: This single-blind clinical trial study was performed o...

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A Comparison of the Antipyretic Effect of Acetaminophen and Ibuprofen in Febrile Children Hospitalized At Amir-Al-Momenin Hospital in Semnan, Iran

Prolonged and high fever may cause various disturbances in children, and prompt lowering of fever is essential. Therefore, an appropriate treatment aimed at rapid lowering of fever and keeping the child afebrile is mandated. There have been various studies on the different types of anti-pyretic treatment in children. The aim of our study is to compare the antipyretic effect of Acetaminophen a...

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The safety of acetaminophen and ibuprofen among children younger than two years old.

BACKGROUND Recently ibuprofen has been introduced as a nonprescription analgesic/antipyretic for use in children. OBJECTIVE To compare the incidence of serious adverse clinical events among children <2 years old given ibuprofen and acetaminophen to control fever. STUDY DESIGN A practitioner-based, randomized clinical trial. A total of 27 065 febrile children were randomized to receive aceta...

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Efficacy and safety of ibuprofen and acetaminophen in children and adults: a meta-analysis and qualitative review.

OBJECTIVE To evaluate the analgesic and antipyretic efficacy and safety of ibuprofen compared to acetaminophen in children and adults. DATA SOURCES Literature searches were performed using PubMed/MEDLINE (through August 2009) and EMBASE (through January 2008) and were restricted to the English language. In PubMed/MEDLINE, search terms used were ibuprofen, acetaminophen, paracetamol, clinical ...

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Antipyretic Effect of Acetaminophen Versus Ibuprofen in Children Referred to the Pediatric Clinic of Imam Reza Hospital (Mashhad)

Introduction: Acetaminophen and ibuprofen are the most widely used drugs in pediatric medicine to control fever and pain. There are different opinions about the effectiveness, duration of effects, and side effects and duration of action in controlling pain and fever of these drugs. In this study, we decided to examine the antipyretic effects of two common drugs to provide solutions based on the...

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تاریخ انتشار 2010