Bioactive silicate nanoplatelets for osteogenic differentiation of human mesenchymal stem cells.

نویسندگان

  • Akhilesh K Gaharwar
  • Silvia M Mihaila
  • Archana Swami
  • Alpesh Patel
  • Shilpa Sant
  • Rui L Reis
  • Alexandra P Marques
  • Manuela E Gomes
  • Ali Khademhosseini
چکیده

Novel silicate nanoplatelets that induce osteogenic differentiation of human mesenchymal stem cells (hMSCs) in the absence of any osteoinductive factor are reported. The presence of the silicate triggers a set of events that follows the temporal pattern of osteogenic differentiation. These findings underscore the potential applications of these silicate nanoplatelets in designing bioactive scaffolds for musculoskeletal tissue engineering.

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عنوان ژورنال:
  • Advanced materials

دوره 25 24  شماره 

صفحات  -

تاریخ انتشار 2013