Role of extracellular [Ca21] in fatigue of isolated mammalian skeletal muscle
نویسندگان
چکیده
SIMEON P. CAIRNS,1,2 WAYNE A. HING,1,3 JOHN R. SLACK,1 ROLAND G. MILLS,4 AND DENIS S. LOISELLE1 1Department of Physiology, School of Medicine, University of Auckland, Auckland; 2Kinesiology Group, School of Physical Education, University of Otago, Dunedin; 3Auckland School of Physiotherapy, Auckland Institute of Technology, Auckland; and 4Department of Physiology, School of Medicine, University of Otago, Dunedin, New Zealand
منابع مشابه
Lactate inhibits Ca21-activated Ca21-channel activity from skeletal muscle sarcoplasmic reticulum
Favero, Terence G., Anthony C. Zable, David Colter, and Jonathan J. Abramson. Lactate inhibits Ca21-activated Ca21-channel activity from skeletal muscle sarcoplasmic reticulum. J. Appl. Physiol. 82(2): 447–452, 1997.— Sarcoplasmic reticulum (SR) Ca21-release channel function is modified by ligands that are generated during about of exercise. We have examined the effects of lactate on Ca21and ca...
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Balog, Edward M., Bradley R. Fruen, Patricia K. Kane, and Charles F. Louis. Mechanisms of Pi regulation of the skeletal muscle SR Ca21 release channel. Am. J. Physiol. Cell Physiol. 278: C601–C611, 2000.—Inorganic phosphate (Pi) accumulates in the fibers of actively working muscle where it acts at various sites to modulate contraction. To characterize the role of Pi as a regulator of the sarcop...
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The possible role of altered extracellular Ca2+ concentration ([Ca2+]o) in skeletal muscle fatigue was tested on isolated slow-twitch soleus and fast-twitch extensor digitorum longus muscles of the mouse. The following findings were made. 1) A change from the control solution (1.3 mM [Ca2+]o) to 10 mM [Ca2+]o, or to nominally Ca2+-free solutions, had little effect on tetanic force in nonfatigue...
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Balog, Edward M., Bradley R. Fruen, Patricia K. Kane, and Charles F. Louis. Mechanisms of Pi regulation of the skeletal muscle SR Ca21 release channel. Am. J. Physiol. Cell Physiol. 278: C601–C611, 2000.—Inorganic phosphate (Pi) accumulates in the fibers of actively working muscle where it acts at various sites to modulate contraction. To characterize the role of Pi as a regulator of the sarcop...
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A possible role of extracellular Cl(-) concentration ([Cl(-)](o)) in fatigue was investigated in isolated skeletal muscles of the mouse. When [Cl(-)](o) was lowered from 128 to 10 mM, peak tetanic force was unchanged, fade was exacerbated (wire stimulation electrodes), and a hump appeared during tetanic relaxation in both nonfatigued slow-twitch soleus and fast-twitch extensor digitorum longus ...
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