Investigation of Biological Property of Nanohydroxyapatite Materials

As it is known, the ceramic and metallic materials, such as Ni-Cr and Co-Cr alloy serve often as a fixed dental materials of restoration in human bones, teeth and vascular stents, but they have a lot of shortcomings, such as they can result in Ni and Cr hypersusceptibility of men and ion exchange between the material and tooth, which lead the distortion and discoloration of the gingival edge and affect also its appearance. Hydroxyapatite (HA) is a main inorganic components in human bones and teeth, and has excellent biocompatibility, biological activity and bone conduction feature[1-6]. As matter of fact, the bone is a kind of flexible and toughening polymer composed of hydroxyapatite-based composites. The composition and structure of artificial-hydroxyapatite are very similar to inorganic components in human bone tissues[4-15], it has a non-toxicity and non-irritant property, and is also non-allergenic, non-mutagenic and carcinogenic, and can generate a chemical reaction with bone to change bone conduction[16-19]. Therefore, nano-hydroxyapatites have Institute of Physical Electron and Life Science and Technology, University of Electronic Science and Technology of China, Chengdu 610054, P.R. China