Prostate Cancer Development and Internal Validation of a Nomogram Predicting the Probability of Prostate Cancer Gleason Sum Upgrading Between Biopsy and Radical Prostatectomy Pathology
نویسندگان
چکیده
Felix K.-H. Chun , Thomas Steuber , Andreas Erbersdobler , Eike Currlin , Jochen Walz , Thorsten Schlomm, Alexander Haese , Hans Heinzer , Michael McCormack , Hartwig Huland , Markus Graefen , Pierre I. Karakiewicz * Department of Urology, University of Hamburg, Hamburg, Germany Martini Clinic– Prostate Cancer Center, University of Hamburg, Hamburg, Germany Department of Pathology, University of Hamburg, Hamburg, Germany Cancer Prognostics and Health Outcomes Unit, University of Montreal, Montreal, Quebec, Canada e u r o p e a n u r o l o g y 4 9 ( 2 0 0 6 ) 8 2 0 – 8 2 6
منابع مشابه
A nomogram to predict Gleason sum upgrading of clinically diagnosed localized prostate cancer among Chinese patients
Although several models have been developed to predict the probability of Gleason sum upgrading between biopsy and radical prostatectomy specimens, most of these models are restricted to prostate-specific antigen screening-detected prostate cancer. This study aimed to build a nomogram for the prediction of Gleason sum upgrading in clinically diagnosed prostate cancer. The study cohort comprised...
متن کاملDevelopment and internal validation of a nomogram predicting the probability of prostate cancer Gleason sum upgrading between biopsy and radical prostatectomy pathology.
OBJECTIVE Previous reports indicate that as many as 43% of men with low grade PCa at biopsy will be diagnosed with high-grade PCa at RP. We explored the rate of upgrading from biopsy to RP specimen in our contemporary cohort, and developed a model capable of predicting the probability of biopsy Gleason sum upgrading. MATERIALS AND METHODS The study cohort consisted of 2982 men treated with RP...
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Background and Objective: Today’s, the Gleason grading system is well known as the world’s most commonly used histological system for prostate cancer. It provides significant information about the prognosis. This prospective paper assessed the correlation of transrectal ultrasound (TRUS) guided biopsy and radical prostatectomy specimens in terms of Gleason scores. In this matter, the effect of ...
متن کاملDevelopment and External Validation of a Nomogram Predicting the Probability of Significant Gleason Sum Upgrading among Japanese Patients with Localized Prostate Cancer
Objective. The aim of this study is to develop a prognostic model capable of predicting the probability of significant upgrading among Japanese patients. Methods. The study cohort comprised 508 men treated with RP, with available prostate-specific antigen levels, biopsy, and RP Gleason sum values. Clinical and pathological data from 258 patients were obtained from another Japanese institution f...
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PURPOSE We determined clinical factors affecting the under grading of biopsy Gleason sum compared with prostatectomy pathology and developed a model predicting the probability of under grading. MATERIALS AND METHODS We analyzed a cohort of 1,701 patients treated for prostate cancer at our institution between 1988 and 2007 with complete biopsy and pathological data available. Patients with a b...
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