3-D Control Over Spatial Heating Using Multi-Element Ultrasound Heating Applicators and Real-Time MR Temperature Feedback
نویسندگان
چکیده
منابع مشابه
Adaptive Volumetric MR-guided High-Intensity Focused Ultrasound Ablations
Introduction Recent technological advances in the field of clinical high intensity focused ultrasound (HIFU) transducer systems and real time MR thermometry using PRF thermometry [1] lead to an increasing trend towards real time feedback control for the MR-guidance of thermal therapies with HIFU. In particular phased array HIFU systems with short beam repositioning times and large aperture/foca...
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PURPOSE Mild hyperthermia (40-45 °C) is a proven adjuvant for radiotherapy and chemotherapy. Magnetic resonance guided high intensity focused ultrasound (MR-HIFU) can non-invasively heat solid tumours under image guidance. Low temperature-sensitive liposomes (LTSLs) release their drug cargo in response to heat (>40 °C) and may improve drug delivery to solid tumours when combined with mild hyper...
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While Magnetic Resonance Thermometry (MRT) has been extensively utilized for non-invasive temperature measurement, there is limited data on the use of high field (≥7T) scanners for this purpose. MR-guided Focused Ultrasound (MRgFUS) is a promising non-invasive method for localized hyperthermia and drug delivery. MRT based on the temperature sensitivity of the proton resonance frequency (PRF) ha...
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Volumetric High Intensity Focused Ultrasound (HIFU) ablation has several advantages as compared to the traditional point-by-point ablation, such as improved energy efficiency and homogeneous thermal lesions with sharp borders [1]. However, there is an increased risk of excessive off-focus heating, especially in the near-field [2], and the thermal lesions can also vary in shape and size due to l...
متن کاملOnline temperature control of focused ultrasound heating using an adaptive PID feedback loop
Introduction Focused ultrasound induced heating for use in thermal therapy requires reliable temperature control to assure safety and therapeutic accuracy. MR thermometry based on the proton resonance frequency shift (PRFS) [1] in combination with a proportional, integral, derivative (PID) feedback control [2] has been suggested as a precise solution for controlling high intensity focused ultra...
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