Commentary: Fungal lifestyle reflected in serine protease repertoire
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Thymus-specific serine protease contributes to the diversification of the functional endogenous CD4 T cell receptor repertoire
Thymus-specific serine protease (TSSP) is a novel protease that may contribute to the generation of the peptide repertoire presented by MHC class II molecules in the thymus. Although TSSP deficiency has no quantitative impact on the development of CD4 T cells expressing a polyclonal T cell receptor (TCR) repertoire, the development of CD4 T cells expressing the OTII and Marilyn transgenic TCRs ...
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