Rare Event Detection Rare Mutation Detection Rare Species Detection
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چکیده
Figure 1: Rare Event Detection includes both Rare Mutation Detection (RMD) and Rare Species Detection (RSD). RMD and RSD can be classified according to their assay components. An RMD assay is comprised of a single primer set plus two competitive probes. RSD utilizes either a single assay to detect a rare species per unit volume (Case 1) or two independent, noncompetitive assays to detect a rare species as a proportion of a more common species (Case 2). Some applications may combine aspects of RMD and RSD.
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