Preoperative parathyroid hormone level as a predictive factor for post-thyroidectomy hypoparathyroidism
نویسندگان
چکیده
Postoperative hypoparathyroidism is one of the most frequent complications after thyroid surgery with the incidence being reported to vary from 1.6% to 50% [1-4]. The causes of the postoperative hypoparathyroidism include surgical trauma to the parathyroid glands, inexperience of the surgeon, hyperthyroidism, retrosternal goiter, extent of neck dissection, and thyroid carcinoma. Post-thyroidectomy hypocalcemia may be categorized into three types according to the symptomatic and biochemical status [5]. Symptomatic and biochemical hypocalcemia is the most significant problem and can progress to the permanent hypocalcemia. Asymptomatic and biochemical hypocalcemia is not a predisposing factor of permanent hypocalcemia. This condition has been presumed to be perioperative hemodilution, or a stunning of parathyroid during the thyroidectomy. Some patients experienced symptomatic and mismatched biochemical hypocalcemia, defined as deOriginal Article Korean Journal of Clinical Oncology 2013;9:28-32 http://dx.doi.org/10.14216/kjco.13005 pISSN 1738-8082 ∙ eISSN 2288-4084
منابع مشابه
Is Decline Rate of Intact Parathyroid Hormone Level a Reliable Criterion for Early Discharge of Patients after Total Thyroidectomy?
Introduction: Parathyroid dysfunction leading to symptomatic hypocalcemia is not uncommon following a total thyroidectomy and is often associated with significant patient morbidity and a prolonged hospital stay. The current study aimed at evaluating the comparative predictive role of serum calcium and intact parathyroid hormone (iPTH) for post-thyroidectomy hypocalcemia. Materials and Methods...
متن کاملValidity of early parathyroid hormone assay as a diagnostic tool for sub-total thyroidectomy related hypocalcaemia.
OBJECTIVE To determine the validity of early (one hour postoperatively) parathyroid hormone (PTH) assay (² 10 pg/ml), keeping gold standard as the serum ionic calcium level, for predicting sub-total thyroidectomy-related hypocalcaemia and to calculate the sensitivity and specificity of latent signs of tetany. STUDY DESIGN Cross-sectional validation study. PLACE AND DURATION OF STUDY Departm...
متن کاملAssociation between Decreased Serum Parathyroid Hormone after Total Thyroidectomy and Persistent Hypoparathyroidism
BACKGROUND Postoperative hypocalcemia caused by hypoparathyroidism is one of the most common morbidities of total thyroidectomy. The aim of this study was to analyze the kinetics and factors affecting PTH levels after total thyroidectomy and central neck dissection (CND). MATERIAL/METHODS We performed a retrospective study in 438 consecutive patients who underwent total thyroidectomy between ...
متن کاملValue of intraoperative parathyroid hormone monitoring in papillary thyroid cancer surgery: can it be used to guide the choice of operation methods?
BACKGROUND To assess the diagnostic value of decreased parathyroid hormone (PTH) in hypoparathyroidism after unilateral operation. METHODS A study was conducted on patients with PTC undergoing total or near-total thyroidectomy plus central neck dissection (CND). RESULTS Postoperative hypocalcemia was found in 42 patients (51.2%). For patients undergoing bilateral CND, those whose tumor inva...
متن کاملOutcome of protracted hypoparathyroidism after total thyroidectomy.
BACKGROUND Although the variables that influence the development of post-thyroidectomy hypocalcaemia are now better understood, the risk factors and long-term outcome of persistent hypoparathyroidism (HPP) are poorly defined. A retrospective review of a prospective protocol for the management of post-thyroidectomy hypocalcaemia was performed. METHODS Patients with a serum calcium level below ...
متن کامل