CALL FOR PAPERS Mitochondrial Function/Dysfunction in Health and Disease Low intrinsic running capacity is associated with reduced skeletal muscle substrate oxidation and lower mitochondrial content in white skeletal muscle
نویسندگان
چکیده
Donato A. Rivas, Sarah J. Lessard, Misato Saito, Anna M. Friedhuber, Lauren G. Koch, Steven L. Britton, Ben B. Yaspelkis III, and John A. Hawley Health Innovations Research Institute, School of Medical Sciences, RMIT University, Bundoora, Australia; Department of Kinesiology, California State University, Northridge, California; Department of Pathology, University of Melbourne, Melbourne, Australia; and Department of Anesthesiology, University of Michigan, Ann Arbor, Michigan
منابع مشابه
Low intrinsic running capacity is associated with reduced skeletal muscle substrate oxidation and lower mitochondrial content in white skeletal muscle.
Chronic metabolic diseases develop from the complex interaction of environmental and genetic factors, although the extent to which each contributes to these disorders is unknown. Here, we test the hypothesis that artificial selection for low intrinsic aerobic running capacity is associated with reduced skeletal muscle metabolism and impaired metabolic health. Rat models for low- (LCR) and high-...
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Garcia-Cazarin ML, Gamboa JL, Andrade FH. Rat diaphragm mitochondria have lower intrinsic respiratory rates than mitochondria in limb muscles. Am J Physiol Regul Integr Comp Physiol 300: R1311–R1315, 2011. First published March 9, 2011; doi:10.1152/ajpregu.00203.2010.—The mitochondrial content of skeletal muscles is proportional to activity level, with the assumption that intrinsic mitochondria...
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