Poster 1014: Omalizumab efficiency in patients with allergic rhinitis and chronic sinusitis

Background Allergic rhinitis (AR) is a very common chronic respiratory disorder and has also been shown to negatively impact quality of life with many comorbiliditys like Chronic rhinosinusitis; There is evidence that IgE antibodies play a role in chronic sinusitis. Investigations have shown that total IgE levels correlate with the severity of sinusitis, as assessed by CT scan. Allergies occur more frequently in patients with chronic sinusitis than in the general population. Omalizumab has shown to be effective for AR in allergen challenge studies and clinical trials. Multiple randomized, double-blind, placebo-controlled studies have shown efficacy of omalizumab in seasonal and perennial AR.