Generation of pseudo-CT from a single MRI for PET/MR attenuation correction purposes
نویسندگان
چکیده
INSERM UMR 1101, LaTIM, Brest, France Current MR attenuation correction (AC) approaches suffer from the lack of precision in the detection of bone and the assigned attenuation coefficients. In general, no unique transformation of MR image intensities into attenuation coefficients exists. The purpose of this work is to derive attenuation coefficient maps from a single MR sequence through the generation of a pseudo-CT map using a derived MRI intensity CT Hounsfield Units (HU) relationship. A retrospective study was undertaken on 10 patients with sequentially performed PET/CT and MR. The LAVA-Flex sequence was investigated, with in-phase (IP) and out-phase (OP) echoes. As a first step, a least square fitting polynomial model (Figure 1) was determined between the CT HU and both MR images (IP and OP) :
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