1 JN - 01168 - 2011 R 2 2 Characterizing the conductance underlying depolarization - 3 induced slow current ( DISC ) in cerebellar Purkinje cells
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چکیده
5 6 Yu Shin Kim, Eunchai Kang, Yuichi Makino, Sungjin Park, Jung Hoon Shin, 7 Hongjun Song, Pierre Launay and David J. Linden 8 9 10 Department of Neuroscience, the Johns Hopkins University School of Medicine, 725 11 N. Wolfe Street, Baltimore, MD 21205, USA; Institute for Cell Engineering, the 12 Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA; 13 Department of Neurology, the Johns Hopkins University School of Medicine, 14 Baltimore, MD 21205, USA; Pre-doctoral Training Program in Human Genetics, 15 the Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA; 16 Institut National de la Santé et de la Recherche Médicale U699, Paris F-75018, 17 France; Equipe Avenir, Institut National de la Santé et de la Recherche Médicale, 18 Paris F-75018, France; Université Paris 7-Denis Diderot, Faculté de Médecine, 19 Site Xavier Bichat, Paris F-75018, France 20 21 22 corresponding authors: 23 24 DJL: 410-614-1529 (voice), 410-614-7334 (FAX), [email protected] 25 YSK: 410-502-2968 (voice), 410-614-6249 (FAX), [email protected] 26 27 Running Head: Characterizing the Purkinje cell DISC conductance 28
منابع مشابه
Characterizing the conductance underlying depolarization-induced slow current in cerebellar Purkinje cells.
Brief strong depolarization of cerebellar Purkinje cells produces a slow inward cation current [depolarization-induced slow current (DISC)]. Previous work has shown that DISC is triggered by voltage-sensitive Ca influx in the Purkinje cell and is attenuated by blockers of vesicular loading and fusion. Here, we have sought to characterize the ion channel(s) underlying the DISC conductance. While...
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