Neural precursor cell chain migration and division are regulated through different β1 integrins
نویسندگان
چکیده
Thomas S. Jacques1, João B. Relvas1, Stephen Nishimura2, Robert Pytela4, Gwynneth M. Edwards3, Charles H. Streuli3 and Charles ffrench-Constant1,5,* 1Wellcome/CRC Institute of Developmental Biology and Cancer, Tennis Court Road, Cambridge, CB2 1QR and Department of Medical Genetics, University of Cambridge, Cambridge, UK 2Department of Anatomic Pathology, University of California San Francisco, CA 94143-0854, USA 3School of Biological Sciences, University of Manchester, Stopford Building, Oxford Road, Manchester, M13 9PT, UK 4Lung Biology Center, University of California San Francisco, CA 94143-0854, USA 5MRC Cambridge Centre for Brain Repair, University Forvie Site, Robinson Way, Cambridge, CB2 2QQ, UK *Author for correspondence (e-mail: [email protected])
منابع مشابه
Neural precursor cell chain migration and division are regulated through different beta1 integrins.
Proliferation and tangential migration of neural precursor cells are essential determinants of CNS development. We have established cell culture models of both these processes using neural precursor cells grown as neurospheres. The pattern of migration that we observe in these cells is homotypic and occurs in the absence of a glial or neuronal scaffold, and is therefore equivalent to that previ...
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تاریخ انتشار 1998