Potassium accumulation frog muscle: the association-induction hypothesis versus the membrane theory.
نویسندگان
چکیده
Zone (4); Santa Barbara Basin, California (5); Lake Biwa, Japan (6); Lake Washington, Washington (7); and the Amazon River (8). It is thought that perylene in these sediments results from the diagenesis of terrestrial pigments which have been rapidly deposited into a reducing sediment. This idea also seems to account for the presence of perylene in this sewage lagoon. We feel it is important not to perpetuate Rose and Harshbarger's suggestion that perylene in this lagoon results from the activity ofjet aircraft when a natural source seems more likely. JOHN G. WINDSOR, JR. ROBERT E. LAFLAMME RONALD A. HITES Department ofChemical Engineering, Massachusetts Institute of Technology, Cambridge 02139
منابع مشابه
Studies on Ion Accumulation in Muscle Cells
A comparison is made between the quantitative predictions of equilibrium ionic distribution in living cells according to the membrane theory (Donnan equilibrium) and according to the association-induction hypothesis. This comparison shows that both theories predict competitive effects of one permeant ion on the equilibrium concentration of another permeant ion; but within the limit of experimen...
متن کاملThe physical state of potassium in frog skeletal muscle studied by ion-sensitive microelectrodes and by electron microscopy: interpretation of seemingly incompatible results.
According to the commonly accepted membrane pump theory most of cellular K+ ions are freely dissolved in free cellular water; the alternative association-induction hypothesis postulates that the bulk of cellular K+ is adsorbed (weakly bound) to cellular proteins that are maintained in a specific labile state in the cytoplasm of a living cell. K+ activities measured with ion-sensitive microelect...
متن کاملEffects of adrenaline, calcium, and ouabain on the resting potential of frog muscle: interpretation based on the theory of allosteric control of cooperative interactions among surface anionic sites.
The surface adsorption theory of the cellular electric potential, a subsidiary of the association-induction hypothesis, can offer quantitative interpretations of the equilibrium resting potential of frog muscle in the presence of a constant concentration (100 mM) of external Na+ and varying external K+ (ranging from 0.1 mM to 100 mM) both in the absence and in the presence of cardinal adsorbent...
متن کاملThallium and cesium in muscle cells compete for the adsorption sites normally occupied by K+.
It was shown that Tl+ can stoichiometrically displace K+ in frog muscle cells. This displacement is independent of the function of cell membrane and postulated pumps and of a macroscopic electric charge or Donnan effect. It follows that Cs+ and Tl+ compete for the adsorption sites normally occupied by K+. On this basis, the association-induction hypothesis predicts that Cs+ and Tl+, like K+, sh...
متن کاملSTUDIES OF IONIC DISTRIBUTION IN LIVING CELLS: IV. EFFECT OF OUABAIN ON THE EQUILIBRIUM CONCENTRATIONS OF Cs',
The equilibrium distribution of CS', Rb', K', Na', and Li+ was studied in normal frog sartorius muscles and in sartorius muscles treated with 3.27 x lo-' M ouabain. The rank order of selectivity was, respectively, R~+>K+xs+>L~+>N~+ for normal muscles and K+>L~+>CS '>R~+>N~+ for ouabain-treated muscles. The data are not readily predictable on the basis of the membrane theory but can be explained...
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ورودعنوان ژورنال:
- Science
دوره 198 4323 شماره
صفحات -
تاریخ انتشار 1977