The effect of age on long-term survival after pancreatic resection for pancreatic cancer

نویسندگان

  • Valentina Beltrame
  • Federico Tona
  • Margherita Moro
  • Carmelo Militello
  • Sergio Pedrazzoli
  • Claudio Pasquali
  • Cosimo Sperti
چکیده

Background The incidence of pancreatic cancer is increasing, and an increasing proportion of patients with pancreatic carcinoma is older than 75 years. After surgical resection remains the treatment of choice for pancreatic neoplasms, an increasing number of elderly patients are being referred for pancreatic resection. Although in the early 1990s there was rarely an indication for major pancreatic resection in the elderly because of the high postoperative complication rate, mortality and limited survival time [1], more recently an acceptable morbidity rate and late outcome in patients with advanced age have been reported [2,3]. This retrospective study analyzed the effect of age on the survival of patients who underwent resection for pancreatic cancer.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Association between alcohol consumption and pancreatic cancer: a systematic review of cohort studies

Background: Among all types of cancers, pancreatic cancer has poor prognosis with 5-year survival below 10%. In theory, alcohol intake may be a modifiable risk factor for pancreatic cancer due to its role in multiple carcinogenic and metabolic signaling pathways. In addition, alcohol consumption may lead to chronic pancreatitis which is underlying cause of pancreatic cancer. However, little is ...

متن کامل

Factors affecting long-term survival after surgical resection of pancreatic ductal adenocarcinoma

PURPOSE Some patients who undergo surgical resection of pancreatic cancer survive longer than other patients. The purpose of this study was to identify the factors that affect long-term survival after resection of histopathologically confirmed pancreatic ductal adenocarcinoma. METHODS A single-center, retrospective study was conducted among 164 patients who underwent surgical resection of pan...

متن کامل

Pancreatic ductal adenocarcinoma: long-term survival does not equal cure.

BACKGROUND Pancreatic ductal adenocarcinoma represents 90% of pancreatic cancers and is an important cause of cancer death in the United States. Operative resection remains as the only treatment providing prolonged survival, but even after a curative resection, 5-year survival rates are low. Our aim was to identify the prognostic factors for long-term survival after resection of pancreatic duct...

متن کامل

Metastatic pulmonary adenocarcinoma 13 years after curative resection for pancreatic cancer: report of a case and review of Japanese literature.

CONTEXT For the majority of patients, ductal adenocarcinoma of the pancreas remains a lethal disease. Currently, surgical extirpation for localized disease offers the only chance for long-term survival. CASE REPORT We report a patient who underwent successful resection of isolated lung metastasis occurring 13 years after pancreatic cancer resection. A 59-year-old woman underwent distal pancre...

متن کامل

Very long-term survival following resection for pancreatic cancer is not explained by commonly mutated genes: results of whole-exome sequencing analysis Running title: Very long-term survival in pancreatic cancer

Author manuscripts have been peer reviewed and accepted for publication but have not yet been edited. share of the royalties received by the University on sales of products related to genes and technologies described in this manuscript. Author manuscripts have been peer reviewed and accepted for publication but have not yet been edited. Pancreatic cancer is a deadly disease in dire need of new ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره 11  شماره 

صفحات  -

تاریخ انتشار 2011