Immunohistochemical localization of RET rearrangements in a Malaysian papillary thyroid carcinoma population.
نویسندگان
چکیده
We found a high prevalence of RET expression among our papillary carcinoma at 77% 08 of 53); p< 0.001. Interestingly, the follicular adenomas and nodular hyperplasia cases exhibited a low expression of RET of 18% (9 of 50 cases) and 22.7% 05 of 66) respectively. RET/PTC re-arrangement has been demonstrated in these lesions before 7,8. It has been postulated that these positive follicular cell represented focal clonal expansion of neoplastic cells.
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ورودعنوان ژورنال:
- The Medical journal of Malaysia
دوره 58 3 شماره
صفحات -
تاریخ انتشار 2003