Facile synthesis of (+/-)-paeonilide.
نویسندگان
چکیده
(+/-)-Paeonilide, a novel monoterpenoid metabolite from the roots of Paeonia delavayi showing anti-platelet activating factor activity, is convergently synthesized in five steps with 59% overall yield. The application of benzoyl peroxide-promoted radical addition of unsaturated ester to aldehyde and subsequent topologically favored cyclization greatly simplified the synthesis.
منابع مشابه
Enantioselective synthesis of (-)-paeonilide.
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ورودعنوان ژورنال:
- The Journal of organic chemistry
دوره 72 10 شماره
صفحات -
تاریخ انتشار 2007