Dantrolene: from better bacon to a treatment for ventricular fibrillation.
نویسندگان
چکیده
Worldwide Epidemiology of Atrial Fibrillation: A Global Burden of Disease 2010 Study Sumeet S. Chugh, MD; Rasmus Havmoeller, MD, PhD; Kumar Narayanan, MD; David Singh, MD; Michiel Rienstra, MD, PhD; Emelia J. Benjamin, MD, ScM; Richard F. Gillum, MD; Young-Hoon Kim, MD; John H. McAnulty, Jr, MD; Zhi-Jie Zheng, MD, PhD; Mohammad H. Forouzanfar, MD; Mohsen Naghavi, MD; George A. Mensah, MD; Majid Ezzati, PhD; Christopher J.L. Murray, MD . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 837
منابع مشابه
Dantrolene versus amiodarone for cardiopulmonary resuscitation: a randomized, double-blinded experimental study
Dantrolene was introduced for treatment of malignant hyperthermia. It also has antiarrhythmic properties and may thus be an alternative to amiodarone for the treatment of ventricular fibrillation (VF). Aim of this study was to compare the return of spontaneous circulation (ROSC) with dantrolene and amiodarone in a pig model of cardiac arrest. VF was induced in anesthetized pigs. After 8 min of ...
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BACKGROUND Resistant ventricular fibrillation, refibrillation. and diminished myocardial contractility are important factors leading to poor survival after cardiac arrest. We hypothesized that dantrolene improves survival after ventricular fibrillation (VF) by rectifying the calcium dysregulation caused by VF. METHODS AND RESULTS VF was induced in 26 Yorkshire pigs for 4 minutes. Cardiopulmon...
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Mrs. Heidari, 53 developed ventricular fibrillation and cardiopulmonary arrest after receiving 15 mL lidocaine 2% for local anesthesia at the Dr. Shariati Hospital Cathlab. There was no identified risk factor for her arrest preoperatively. She had a history of exertional chest pain for about 5 years and an electrocardiogram showed only inverted T-waves at the time of angiography. The case i...
متن کاملDantrolene Improves Survival Following Ventricular Fibrillation by Mitigating Impaired Calcium Handling in Animal Models Running title: Zamiri et al.; Improving survival from VF by dantrolene
University of Toronto, Toronto; Keenan Research Centre, Li Ka Shing Knowledge Institute, St Michael’s Hospital, Toronto; Institute of Medical Science, University of Toronto, Toronto; Dept of Physiology, University of Toronto, Toronto, ON, Canada; Institute LIRYC, Université Bordeaux 1, Bordeaux, France; Institute for Computational Medicine, Dept of Biomedical Engineering, Johns Hopkins Universi...
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ورودعنوان ژورنال:
- Circulation
دوره 129 8 شماره
صفحات -
تاریخ انتشار 2014