The Progestin DMPA is associated with increased CD 3 and CD 4 T - Lymphocytes among women living with HIV

DMPA is associated with increased CD 3 and CD 4 T - Lymphocytes among women living with HIV

67-69 Sangi

implant and DMPA appears increasingly important in light of one recent animal study suggesting a relationship between progestin exposure and vaginal atrophy (which might lead to increased risk of HIV infection).6 Although it is premature to extrapolate the findings of this study to humans, the results highlight the importance of correct and consistent condom use among users of hormonal contrace...

T Lymphocytes in AIDS Patients With Tuberculosis

CD 4 + and CD 8 + T lymphocyte counts, naive and memory/effector CD 4 + T subpopulations, and the expression of CD 38 on CD 8 + T lymphocytes were evaluated in four groups: AIDS patients with tuberculosis (HIV/TB, n=14), HIV-1 infected patients (HIV, n=10), HIV-1 negative patients with tuberculosis (TB, n=20) and healthy controls (CTL, n=17). TB and HIV had fewer CD 4 + T cells than CTL, with t...

Update to CDC’s U.S. Medical Eligibility Criteria for Contraceptive Use, 2016: Revised Recommendations for the Use of Hormonal Contraception Among Women at High Risk for HIV Infection

CDC's U.S. Medical Eligibility Criteria for Contraceptive Use (U.S. MEC) (first published in 2010 and updated in 2016) provides evidence-based guidance for the safe use of contraceptive methods among U.S. women with certain characteristics or medical conditions (1), and is adapted from global guidance from the World Health Organization (WHO) and kept up to date based on continual review of publ...

Decreased tissue inhibitor of metalloproteinase in the endometrium of women using depot medroxyprogesterone acetate: a role for altered endometrial matrix metalloproteinase/tissue inhibitor of metalloproteinase balance in the pathogenesis of abnormal uterine bleeding?

BACKGROUND Abnormal uterine bleeding is commonly associated with progestin-only contraceptives, including depot medroxyprogesterone acetate (DMPA), and remains the main reason why these agents are discontinued. Matrix metalloproteinases (MMP), enzymes which degrade specific extracellular matrix components, and leukocytes are implicated in menstruation. Alteration in endometrial MMP-9 and leukoc...