Significance of late reactions after bronchial challenge with house dust mite.

SQ-standardized house dust mite immunotherapy as an immunomodulatory treatment in patients with asthma

BACKGROUND   Specific immunotherapy is the only treatment with the potential to prevent progression of the allergic disease and the potential to cure patients. The immunomodulatory ability of SQ-standardized house dust mite (HDM) subcutaneous immunotherapy (SCIT) was investigated in patients with allergic asthma. METHODS Fifty-four adults with HDM-allergic asthma were randomized 1:1 to receiv...

A Study on Late Allergic Reactions to House Dust Mite in Bronchial Asthmatics*

Relation between skin tests, inhalation tests, and histamine release from leucocytes and IgE in house-dust mite allergy.

This study was concerned with the correlation between skin test, bronchial provocation test, and histamine release from leucocytes and the serum level of total and allergen-specific IgE in patients atopic to house-dust mite allergen (Dermatophagiodes pteronyssinus) as measured by an intracutaneous skin test. It is concluded that, assuming a positive provocation test to be evidence of allergy, e...

House-dust mite asthma. Results of challenge tests on five criteria with Dermatophagoides pteronyssinus.

Twenty-eight patients with asthma and house-dust allergy were investigated by five different challenge tests with mite extract (Dermatophagoides pteronyssinus). These tests were performed on the skin, bronchi, nasal mucosa, and leucocytes, and on normal human lung tissue passively sensitized by the patients' serum. The results were compared with each other and with the clinical state of the pat...

Interleukin-5 and eosinophil cationic protein in nasal lavages of rhinitis patients.

The production of interleukin-5 and eosinophil cationic protein (ECP) in the nasal cavity was examined in 24 patients with rhinitis who were allergic to the house dust mite. During a double-blind placebo-controlled cross-over study, fluticasone propionate aqueous nasal spray (200 micrograms) was administered twice daily for 2 weeks. After four basal nasal lavages provocation with house dust mit...