Nitrogen mustard and triethylene melamine content in normal and tumor tissues after intra-arterial and intravenous injection in rats.

Study of the Effects of Hexamethylentetramine on Decrease of Defects of the Lung Tissue in the Rat Exposed to Sulfur Mustard

Purpose: The aim of this study was to evaluate the effects of HMT on protection of lung tissue exposed to HD in the rat. Materials and Methods: In this study twenty Albino Wister adult male rats weighting 200±20 gram were used. Rats divided randomly into 4 groups (each group has 5 rats) as below: Normal saline group (NS), HMT group, HD group (0.25% HD) and HD+HMT group. Normal saline and HD sol...

New therapy for leukemia, polycythemia, and lymphoma.

X-radiation remains the treatment of choice in most cases of leukemia and lymphoma, but new agents are playing an increasing role in therapy. Radioactive phosphorus does not produce radiation sickness and results with it are comparable to those of x-ray therapy in chronic leukemia. Urethane and nitrogen mustard may produce remissions in patients with chronic leukemia who have become resistant t...

Protective effects of rosuvastatin against hyperglycemia-induced oxidative damage in the pancreas of streptozotocin-induced diabetic rats

Introduction: According to the powerful antioxidant effects of rosuvastatin, the present study aimed to examine the protective effects of rosuvastatin against oxidative damage of diabetic pancreas by potentiation of the antioxidant capacity in streptozotocin-induced diabetic rats. Methods: Experiment was performed in four groups of male Wistar rats (n=6 in each group): normal, diabetic and ...

Triethylene melamine in the treatment of neoplastic disease; a compound with nitrogen-mustardlike activity suitable for oral and intravenous use.

Effect of cell division inhibition on the phosphorus metabolism of growing cultures of Saccharomyces cerevisiae.

Radiation and certain organic chemicals, under appropriate experimental conditions, may selectively inhibit cell division but not growth of cultures of Saccharomyces cerevisiae which are in the logarithmic stages of both growth and division (Lea et al., 1937; Spoerl et al., 1954; Loveless et al., 1954). The inhibition of cell division (multiplication) without a concommitant inhibition of growth...