Neuroprotective potential of Withania somnifera in cerebral ischemia
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چکیده
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منابع مشابه
Neuroprotective effects of Withania coagulans root extract on CA1 hippocampus following cerebral ischemia in rats
Objective: Oxygen free radicals may be implicated in the pathogenesis of ischemia reperfusion damage. The beneficial effects of antioxidant nutrients, as well as complex plant extracts, on cerebral ischemia-reperfusion injuries are well known. This study was conducted to determine the effects of the hydro-alcoholic root extract of Withania coagulans on CA1 hippocampus oxidative damages followin...
متن کاملStudy of Withania somnifera with the spatial reference of phytochemical, FTIR and flavonoids quantification
Plant is oldest existing complete medical significance in the world. Its origins go back nearly 5000 years. In this research article make known on Withania somnifera (Ashwagandha) as Medicinal plants have therapeutic potential due to the presence of natural antioxidants functioning as reducing agents, free radical scavengers and quenchers of singlet oxygen. Majority of different medicinal plant...
متن کاملNeuroprotective effects of Withania somnifera Dunn. in hippocampal sub-regions of female albino rat.
The neuroprotective effects of W. somnifera were studied on stressed adult female Swiss albino rats. Experimental rats were subjected to immobilization stress for 14 h and were treated with a root powder extract of W. somnifera available as Stresscom capsules (Dabur India Ltd). Control rats were maintained in completely, non stressed conditions. Thionin stained serial coronal sections (7 microm...
متن کاملInternational Journal of Biopharmaceutics
The present study investigates the effect of Withania somnifera (WS), a well-known adaptogenic agent in Indian system of Medicine, on acute cerebral reperfusion and long-term cerebral hypoperfusion in rats. Acute ischemiareperfusion (30 min occlusion of bilateral common carotid arteries followed by 45 min. reperfusion) and Long-term cerebral hypoperfusion (for 15 days) in C.F. strain rats were ...
متن کاملWithania somnifera Induces Cytotoxic and Cytostatic Effects on Human T Leukemia Cells
Cancer chemotherapy is characterized by an elevated intrinsic toxicity and the development of drug resistance. Thus, there is a compelling need for new intervention strategies with an improved therapeutic profile. Immunogenic cell death (ICD) represents an innovative anticancer strategy where dying cancer cells release damage-associated molecular patterns promoting tumor-specific immune respons...
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تاریخ انتشار 2016