Papule on the dorsal foot.

Acquired hyperpigmented lesion on the foot

case: A 3.5-year-old girl presented with a 1-year history of a slow growing pigmented lesion on the dorsal aspect of her right foot. Physical examination revealed the presence of a pigmented patch with color distribution from pink to tan to dark brown, relatively well circumscribed and approximately 1.5 × 2cm with irregular borders, and especially a single dark central papule superimposed...

NMDA glutamate receptor inhibition in the dorsal hippocampus reduced the maintenance of electric foot shock stress -induced anxiety and depression like behaviors in mice

Introduction: In the present study, the effect of inhibition of glutamate NMDA receptors located in the dorsal hippocampus on the maintenance of anxiety and depression like behaviors induced by electric foot shock stress was investigated. Materials and Methods: NMARI male mice were divided into two categories. The first category received electro foot shock for 30 minutes after injection of mema...

Treatment of the Mirror Foot with Central Ray Resection: Report of 2 Cases

The mirror foot is a rare congenital foot anomaly which is often associated with 6- to 8-toed polydactyly. Postaxial polydactyly is the most common form of this anomaly, while central polydactyly is seen infrequently. We report on 2 cases of the central mirror-foot anomaly. Calcaneus duplication and fibular hypoplasia were present in 1 case. We treated both patients by resecting the middle foot...

A pink papule on the forehead of a young woman

Tender Papule Rising on the Digit: Pacinian Neuroma Should Be Considered in Differential Diagnosis

Pacinian corpuscles are sensory nerve-end organs located in the deep dermis and subcutaneous tissue of the palms or soles. Pacinian neuroma is an extremely rare feature, defined as hyperplasia or hypertrophy of Pacinian corpuscles. About half of Pacinian neuromas present with point tenderness. There have been a limited number of cases reported around the world. We observed a 45-year-old woman w...