Low-dose DDAVP in nocturnal enuresis.
نویسندگان
چکیده
A five-year experience with the vasopressin analogue desmopressin acetate (DDAVP) for nocturnal enuresis is described in 59 children. The initial starting dose of 5 micrograms at bedtime is lower than that reported in other series. Eighty-one percent of patients required 10 micrograms or less to achieve improvement or resolution of bedwetting.
منابع مشابه
EVect of DDAVP on nocturnal enuresis in a patient with nephrogenic diabetes insipidus
The case of an 8 year old boy with both nocturnal enuresis and nephrogenic diabetes insipidus is presented. Diagnosis of nephrogenic diabetes insipidus was based on a typical medical history, the characteristic result of a fluid restriction test, the lack of an eVect of 1-desamino-8D-arginine (DDAVP) on both urine osmolality and plasma coagulation factors and, finally, the detection of a hemizy...
متن کاملPlasma vasopressin and response to treatment in primary nocturnal enuresis.
AIMS To examine the relation between nocturnal vasopressin release and response to treatment with the vasopressin analogue 1-desamino-8-D-arginine vasopressin (DDAVP) in children with primary monosymptomatic nocturnal enuresis. DESIGN Children were recruited from a specific enuresis clinic and entered into a defined treatment programme. Nocturnal vasopressin concentrations were measured every...
متن کاملEffect of DDAVP on nocturnal enuresis in a patient with nephrogenic diabetes insipidus.
The case of an 8 year old boy with both nocturnal enuresis and nephrogenic diabetes insipidus is presented. Diagnosis of nephrogenic diabetes insipidus was based on a typical medical history, the characteristic result of a fluid restriction test, the lack of an effect of 1-desamino-8-D-arginine (DDAVP) on both urine osmolality and plasma coagulation factors and, finally, the detection of a hemi...
متن کاملDesmopressin has an influence on the arousability of children with primary nocturnal enuresis.
PURPOSE Several studies provide evidence regarding the effect of desmopressin (DDAVP) on the sleep of adults. Therefore, we investigate whether this effect has a role in children with primary nocturnal enuresis treated intranasally with DDAVP. MATERIALS AND METHODS A prospective, randomized, placebo controlled, double-blind, crossover study was performed. Patients were assigned to 2 groups by...
متن کاملDDAVP and urine osmolality in refractory enuresis.
A double blind crossover trial of 20 micrograms intranasal 1-deamino-8-d-arginine vasopressin (DDAVP) versus placebo was carried out in 17 children with intractable enuresis aged between 6 and 13 years who had failed to respond to drugs and an enuresis alarm. Fluid intake was not restricted. There was a significant reduction in the number of wet nights. Seven children (41%) were cured or showed...
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ورودعنوان ژورنال:
- Clinical pediatrics
دوره 31 5 شماره
صفحات -
تاریخ انتشار 1992