Cardiopulmonary Resuscitation with Chest Compressions during Sustained Inflations: A New Technique of Neonatal Resuscitation that Improves Recovery and Survival in a Neonatal Porcine Model Running title: Schmölzer et al.; Compressions and sustained inflations in newborns

نویسندگان

  • Georg M. Schmölzer
  • Megan O'Reilly
  • Shaun Cowan
  • Sharon Qin
  • David L. Bigam
چکیده

Me Me M di di dic ca cal l Un Un Univ iv iver er e si si sity ty ty G G Gra ra raz, z, G G Gra ra raz, z, z A A Aus us str tr tria ia ia Abstract Background—Guidelines on neonatal resuscitation recommend 90 chest compressions (CC) and

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Cardiopulmonary resuscitation with chest compressions during sustained inflations: a new technique of neonatal resuscitation that improves recovery and survival in a neonatal porcine model.

BACKGROUND Guidelines on neonatal resuscitation recommend 90 chest compressions (CCs) and 30 manual inflations (3:1) per minute in newborns. The study aimed to determine whether CC s during sustained inflations (SIs) improves the recovery of asphyxiated newborn piglets in comparison with coordinated 3:1 resuscitation. METHODS AND RESULTS Term newborn piglets (n=8/group) were anesthetized, int...

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Chest compression during sustained inflation: hypoxic and oxidative stress

Current recommendation for chest compressions in neonatal resuscitation is to use a coordinated 3:1 ratio of chest compressions to ventilations (C:V), interrupting every third compression to deliver an assisted ventilation. Despite this recommendation, the evidence is still unclear on the optimal C:V ratio for use in neonates. Our team has previously reported a novel technique of sustained infl...

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Improving neonatal cardiopulmonary resuscitation hemodynamics: are sustained inflations during compressions the answer?

C hest compressions are rarely needed in newly born infants, with an estimated occurrence of 0.08% for near-term and term deliveries; however, the consequences of a hypoperfused state on the brain and other organ systems can be devastating. 1 Newborns that require prolonged cardiac compressions with no signs of life beyond 10 minutes are at risk for exceptionally poor outcomes, with up to 83% m...

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Return of spontaneous Circulation Is Not Affected by Different Chest Compression Rates Superimposed with Sustained Inflations during Cardiopulmonary Resuscitation in Newborn Piglets

OBJECTIVE Recently, sustained inflations (SI) during chest compression (CC) have been suggested as an alternative to the current approach during neonatal resuscitation. However, the optimal rate of CC during SI has not yet been established. Our aim was to determine whether different CC rates during SI reduce time to return of spontaneous circulation (ROSC) and improve hemodynamic recovery in ne...

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Neonatal resuscitation: evolving strategies

Birth asphyxia accounts for about 23% of the approximately 4 million neonatal deaths each year worldwide (Black et al, Lancet, 2010, 375(9730):1969-87). The majority of newborn infants require little assistance to undergo physiologic transition at birth and adapt to extrauterine life. Approximately 10% of infants require some assistance to establish regular respirations at birth. Less than 1% n...

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تاریخ انتشار 2013