Herpes simplex vaccines.
نویسنده
چکیده
Prospects for the development of vaccines against herpes simplex virus types 1 and 2 and other herpesvirus group vaccines are discussed from the scientific, medical, and economic standpoints. Probably, the most practical development will be glycoprotein subunit vaccines, prepared from herpes simples virus types 1 and 2, that will be tested for prophylaxis and therapy of acute viral disease and for cancer that may be caused by these agents.
منابع مشابه
The Changing Epidemiology of Herpes Simplex Virus Type 1 Infection: The Associated Effects on the Incidence of Ocular Herpes
Herpes simplex virus type 1 (HSV-1) with a worldwide distribution has been reported in all human populations, resulting in a clinical spectrum of infections. Although HSV type 2 (HSV-2) is known as the most common cause of genital herpes, an increasing number of cases with genital herpes are caused by HSV-1. The present study aimed to discuss the changes in the epidemiology of HSV-1 infection i...
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OBJECTIVES To summarise the current status of genital herpes simplex virus (HSV) vaccine development and provide a discussion of the potential benefits and limitations of genital herpes vaccines. METHODS Literature review. RESULTS Genital herpes simplex virus infection has a complex pathogenesis that has contributed to it becoming a serious worldwide problem. In an attempt to control the pr...
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Modified herpes simplex viruses that are unable to produce glycoprotein D may make effective vaccines.
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The immunology of herpes simplex infections has been reviewed, particularly in relation to potential herpes simplex virus (HSV) vaccines, and to the association between HSV and cervical cancer. Relevant data from humans, experimental animals, and in vitro systems implicate both specific immune mechanisms and nonspecific factors in the course of HSV infections. There appear to be complex interac...
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The immunology of herpes simplex infections has been reviewed, part icularly in relation to potential herpes simplex virus (HSV) vaccines, and to the association between HSV and cervical cancer. Relevant data from humans, experimental animals, and in v i t r o systems implicate both specific immune mechanisms and nonspecif ic factors in the course of HSV infections. There appear to be complex i...
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ورودعنوان ژورنال:
- Cancer research
دوره 36 2 pt 2 شماره
صفحات -
تاریخ انتشار 1976