Next-generation digital information storage in DNA.

نویسندگان

  • George M Church
  • Yuan Gao
  • Sriram Kosuri
چکیده

Digital information is accumulating at an astounding rate, straining our ability to store and archive it. DNA is among the most dense and stable information media known. The development of new technologies in both DNA synthesis and sequencing make DNA an increasingly feasible digital storage medium. We developed a strategy to encode arbitrary digital information in DNA, wrote a 5.27-megabit book using DNA microchips, and read the book by using next-generation DNA sequencing.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Use of DNA for Computation , Storage and Cryptography of Information

26 Abstract— DNA computing was proposed [1] as a method of solving a group of inflexible computational tribulations in which the computing time can grow up exponentially with respect to the problem size. A DNA can also be used as a next generation Digital Information Storage Medium that has tremendous storage capacity and low maintenance cost. This process of artificial manufacturing and decodi...

متن کامل

TextMess 2.0: Las Tecnologías del Lenguaje Humano ante los nuevos retos de la comunicación digital

The overall aim of this project focuses on the study, development and experimentation with different techniques and systems based on Human Language Technologies (HLT) for developing the next generation of intelligent digital information processing systems (modelling, retrieval, processing, comprehension and detection), in order to meet the present challenges posed by digital media. In this new ...

متن کامل

I-37: Establishing High Resolution Genomic Profiles of Single Cells Using Microarray and Next-Generation Sequencing Technologies

The nature and pace of genome mutation is largely unknown. Standard methods to investigate DNA-mutation rely on arraying or sequencing DNA from a population of cells, hence the genetic composition of individual cells is lost and de novo mutation in cell(s) is concealed within the bulk signal. We developed methods based on (SNP-) arraying and next-generation sequencing of single-cell whole-genom...

متن کامل

Strategies and Clinical Applications of Next Generation Sequencing

Abstract DNA sequencing is one of the great valuable techniques in molecular biology, which can be used to detect the sequence of nucleotides in a DNA fragment. The high-throughput se­quencing known as Next Generation Sequencing (NGS) revolutionized genomic research and molecular biology; therefore, the whole human genome can be sequenced with a low cost in several days. NGS technology is simi...

متن کامل

The role of a digital librarian in the management of digital information systems (DIS)

Stresses that the multimedia nature of the next generation of digital libraries requires the digital librarians (DL) to be essentially a type of specialist librarian who has to manage and organize the digital library, handle the specialized tasks of massive digitization, storage, access, digital knowledge mining, digital reference services, electronic information services, search co-ordination,...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Science

دوره 337 6102  شماره 

صفحات  -

تاریخ انتشار 2012