Allergy to cow's milk protein and reaction to methylprednisolone – case study

Background Certain foods are used as excipients in pharmacological products. Thus, patients with lgE-mediated food allergy could present reaction to the pharmacological product whose the excipient is the food in question. Such reactions are rare, considering the small quantity of food protein present in the products. In most situations, these medicines need not be avoided in patients with food allergy, as most tolerate the medication without complications. Reactions to the drugs in patients with allergy to cow’s milk protein (CMPA) are scarcely reported. Generally the lactose is not contaminated with milk protein, but this could happen in rare situations. There are reports of two patients with high levels of lgE to cow’s milk that presented urticarial after receiving methylprednisolone.