Acute Coronary Syndromes Compendium
نویسنده
چکیده
There are currently almost no genetic data associated with the acute coronary syndromes of unstable angina or myocardial infarction (MI). The only documented genetic variants associated with increased risk for MI, per se, are the A and B blood group variants. There are no genetic data differentially associated with ST segment elevation MI or non-ST segment elevation MI. Genetic variants predisposing specifically to plaque rupture are yet to be detected. The following review is primarily on the genetic risk variants predisposing to coronary atherosclerosis, the process underlying the acute coronary syndromes.
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Acute Coronary Syndromes Compendium
Coronary heart disease (CHD) and other manifestations of atherosclerosis were not among the most common causes of death until the beginning of the 20th century, but thereafter a dramatic increase was observed in industrialized countries, including Western Europe and the United States, peaking around 1960 to 1980. Comparable increases in the incidence of CHD have later occurred or are currently ...
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