Mucosal-dominant pemphigus vulgaris in a captopril-taking woman with angioedema*
نویسندگان
چکیده
We describe a 39-year-old woman with an apparent captopril-induced, contact mucosal-dominant pemphigus vulgaris and angioedema, who took captopril during a bout of arterial hypertension. This exposure suggests that captopril and pathophysiology of angioedema stimulated the development of pemphigus vulgaris, which was diagnosed using the novel, indirect immunofluorescence BIOCHIP mosaic, with the modification to detect serum IgG4 autoantibodies. We discuss the patient, who experienced a chain of events leading to the active stage of pemphigus vulgaris, and review concepts of pemphigus vulgaris inducible by drugs and pathological immunity.
منابع مشابه
آنژیوادم متعاقب مصرف داروی کاپتوپریل: یک مطالعه موردی
Angioedema is a rare disease with autosomal dominant is largely complement system. This disease is characterized by non-itchy mucocutaneous and non-pitting edema. In some cases, this disease appears as a result of Captopril intake which is orally and sublingually used in the treatment of severe hypertension. In this study, angioedema as a rare complication of Captopril sublingual intake was ...
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