Dimethylformamide and alcohol intolerance.
نویسندگان
چکیده
Facial flushing and other symptoms were reported by 19 of a group of 102 men who worked with dimethylformamide (DMF). Twenty-six of the 34 episodes occurred after the workers had consumed alcoholic drinks. The metabolite N-methylformamide (MF) was detected in the urine on 45 occasions, the highest recorded concentration being 77 microliter/litre. The highest recorded concentration of DMF in air was 200 ppm. The DMF-ethanol reaction is possibly attributable to the inhibition of acetaldehyde metabolism, probably by MF.
منابع مشابه
Acidic properties of some 1,2,4-triazole derivatives in non-aqueous media
Some 1,2,4-triazole derivatives were titrated potentiometrically with tetrabutylammonium hydroxide in four non-aqueous solvents such as isopropyl alcohol, N,N-dimethylformamide (DMF), tert-butyl alcohol and acetonitrile, and the half-neutralization potential values and the corresponding pKa values were determined for all cases.
متن کاملElectrocarboxylation in supercritical CO2 and CO2-expanded liquids
In this study, the electroc of dimethylformamide (D stainless steel cathode w rod or a platinized platin tetrakis(decyl)ammonium boxylation was carried ou ranging from 0.1 to 150 m solubility of the supporti best results were obtained oretical amount of electri with an 82.4% phenylaceti bibenzyle, benzyl alcohol
متن کاملFear of heights and mild visual height intolerance independent of alcohol consumption
Background Visual height intolerance occurs when a visual stimulus causes apprehension of losing balance and falling from some height. Affecting one-third of the population, it has a broad spectrum of symptoms, ranging from minor distress to fear of heights, which is defined as a specific phobia. Specific phobias are associated with higher alcohol consumption. This has not been specifically sho...
متن کاملAlkylation of Theobromine: Preparation of Isopropyl and sec-butyl- theobromines using N, N-dimethylformamide as Solvent
N-isopropyltheobromine and N-sec-butyltheobromine were synthesized via nucleophilic substitution reaction by reacting theobromine and two kind of alkyl bromide derivatives, i.e. isopropyl bromide and sec-butyl bromide using N, Ndimethylformamide (DMF) as a solvent. Yields (N-isopropyltheobromine = 7.70%; N-sec-butyltheobromine = 5.89%) were slightly less than the previous synthesis which used e...
متن کاملSupercritical Water Oxidation (SCWO) for Hazardous Waste Destruction: Enhanced Removal of N-Containing Hydrocarbons by Using Isopropyl Alcohol (IPA)
This work is about supercritical water oxidation (SCWO) for the removal of hazardous hydrocarbons in wastewater, otherwise treated by incineration. It has been found that the addition of alcohol improves the hydrocarbon conversion; shifting the reaction towards final benign products. The compound under investigation is N, N Dimethylformamide (DMF) undergoing SCWO in the presence of isopropyl al...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- British journal of industrial medicine
دوره 36 1 شماره
صفحات -
تاریخ انتشار 1979