THE HYPOXIC HEMATOPOIETIC STEM CELL NICHE Consequences of Hypoxia- induced Transcription on Stem Cell Fate Rehn, Matilda
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منابع مشابه
Hypoxic induction of vascular endothelial growth factor regulates murine hematopoietic stem cell function in the low-oxygenic niche.
Hypoxia is emerging as an important characteristic of the hematopoietic stem cell (HSC) niche, but the molecular mechanisms contributing to quiescence, self-renewal, and survival remain elusive. Vascular endothelial growth factor A (VEGFA) is a key regulator of angiogenesis and hematopoiesis. Its expression is commonly regulated by hypoxia-inducible factors (HIF) that are functionally induced i...
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تاریخ انتشار 2017