Proteo-lipobeads for the oriented encapsulation of membrane proteins.

نویسندگان

  • Pinar Frank
  • Bernhard Siebenhofer
  • Theresa Hanzer
  • Andreas F Geiss
  • Florian Schadauer
  • Ciril Reiner-Rozman
  • Bill Durham
  • Leslie M Loew
  • Bernd Ludwig
  • Oliver-M H Richter
  • Christoph Nowak
  • Renate L C Naumann
چکیده

As a surrogate of live cells, proteo-lipobeads are presented, encapsulating functional membrane proteins in a strict orientation into a lipid bilayer. Assays can be performed just as on live cells, for example using fluorescence measurements. As a proof of concept, we have demonstrated proton transport through cytochrome c oxidase.

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عنوان ژورنال:
  • Soft matter

دوره 11 15  شماره 

صفحات  -

تاریخ انتشار 2015