Sweet fruit from a poisonous kiss

نویسنده

  • Delong Liu
چکیده

Editorial Acute promyelocytic leukemia (APL), once a rapidly fatal disease, has become most curable of all leukemias, thanks to the two Chinese wonder drugs, all-trans retinoid acid and arsenic trioxide (AT). PML-RXARa fusion protein is the hallmark and driving force of APL. In the April 9 issue of the journal, Science, Zhang et al. provided new and convincing evidence on how AT, an ancient poisonous medicine, plays the tricks on the oncoprotein, PML-RARa, and sheds lights on how a poisonous kiss leads to the sweet fruit [1].

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عنوان ژورنال:

دوره 3  شماره 

صفحات  -

تاریخ انتشار 2010