The Effect of Volatile Anesthetics on Giant Neurons in the Lobula Plate in the Fly
نویسنده
چکیده
Movement sensitive giant neurons in the lobula plate of the fly (H,-neurons, V-neurons) are affected by low con centrations of volatile anesthetics (halothane, N20): the spike frequency generated by motion in the preferred di rection decreases, that in the opposite direction increases. This means that the response to the motion stimulus de fined as the spike frequency modulation decreases. Higher concentrations of the anesthetics lead to an increasing spike frequency which is unaffected by the motion stimulus, until eventually no spikes are generated any longer. The results are in agreement with the assumption that the anesthetics increase the membrane permeability of these neurons.
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