A case of immunoglobulin G4-related respiratory disease with multiple lung cysts: A case report
نویسندگان
چکیده
A 48-year-old man was admitted for evaluation of abnormal shadows on chest radiograph. Chest computed tomography (CT) showed cysts, nodules, and cervical and axillary lymphadenopathies. Elevated serum levels of IgG4 and interleukin (IL)-6 suggested IgG4-related disease (IgG4-RD) or multicentric Castleman's disease (MCD). Histologic findings of the cervical lymph node and right lung S6 biopsies revealed numerous IgG4-positive plasma cells. Although CT findings of the lungs were atypical for IgG4-RD, consistent histologic findings, clinical symptoms, and laboratory data made us conclude IgG4-RD. Because histologic findings of IgG4-RD and MCD have similarities, differentiating between the two diseases should consider the clinical presentation.
منابع مشابه
A Rare Case Report with Periorbital Edema
IgG4 related disease is fibro-inflammatory condition characterized by infiltration and increased levels of G4 immunoglobulin, multi-organ involvement and periorbital swelling. It is more common among men especially in middle to old ages. The diagnosis should be confirmed with histopathology. The diagnostic three important features of disease are lymphoplasmacytic infiltration, storiform fibrosi...
متن کاملCoexistence of lung cancer and immunoglobulin G4-related lung disease in a nodule: a case report.
BACKGROUND Immunoglobulin G4-related disease is characterized by infiltration of immunoglobulin G4-positive plasmacytes in various organs. The radiological findings of lung involvement of immunoglobulin G4-related disease include hilar and mediastinal lymphadenopathies, thickness of bronchovascular bundles, peribronchovascular consolidation, and lung nodules. Although a pathological approach is...
متن کاملInflammatory pseudotumors of the kidney and the lung presenting as immunoglobulin G4-related disease: a case report
INTRODUCTION It has been reported that immunoglobulin G4-related systemic disease can spread to nearly every organ, and often presents as an inflammatory mass or masses at those sites. In the kidney, this disease is often diagnosed after a radical or partial nephrectomy following the discovery of an inflammatory mass which is often suspected to be a malignant tumor. Here, we present a rare case...
متن کاملLarge Hydatid Cyst of Ovary A Very Rare Case Report
Human hydatid cyst is a wide spread disease. It is an endemic disease in Iran. Hydatid cyst is extremely rare in the female reproductive organs. This is a case report of ovarian hydatid cyst in a 42-year-old woman. She presented with feeling of enlargement of abdomen and abdominal pain. On physical examination, a large mass in lower abdomen palpated. Ultrasonography reported a heterogeneous ...
متن کاملNonspecific Interstitial pneumonia (NSIP)/ Overlap or Distinct Entity: A case report from the National Research Institute of Tuberculosis and Lung Disease (NRITLD)
Background: In many cases of ILD (interstitial lung disease), overlap diagnosis is considered. Here, a few cases with diagnosis of a variety of ILDs, where eventual open lung biopsy has been performed are selected. Reference will be made to reliable sources to show that NSIP can still be a variant of UIP (Usual interstitial pneumonia) with better treatment response and prognosis. Case Presenta...
متن کامل