Title A simple bias correction in linear regression for quantitative trait association under two-tail extreme selection
نویسندگان
چکیده
Selective genotyping can increase power in quantitative trait association. One example of selective genotyping is two-tail extreme selection, but simple linear regression analysis gives a biased genetic effect estimate. Here, we present a simple correction for the bias.
منابع مشابه
A Simple Bias Correction in Linear Regression for Quantitative Trait Association Under Two-Tail Extreme Selection
Selective genotyping can increase power in quantitative trait association. One example of selective genotyping is two-tail extreme selection, but simple linear regression analysis gives a biased genetic effect estimate. Here, we present a simple correction for the bias.
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