Methods in Enzymology

Editors-in-Chief: SIDNEY P. COLOWICK and NATHAN 0. KAPLAN VOLUME 51: PURINE AND PYRIMIDINE NUCLEOTIDE METABOLISM Edited by PATRICIA A. HOFFEE and MARY ELLEN JONES Surveying the last decade's significant advances conSECTION HEADINGS: BIOSYNTHETIC ENZYMES. Activacerning the enzymology of purine and pyrimidine metabotion of Ribose Phosphate. De Novo Pyrimidine Biosynthelism and the development of new procedures to study sis: Single Enzymes; Enzyme Complexes. DeNovo Purine such enzymology, Volume 51 of Methods in Enzymology Biosynthesis. Deoxynucleotide Synthesis. DEGRADATIVE is the only available publication that covers the area in AND SALVAGE ENZYMES: Nucleotidases and Nucleosisuch detail and scope. In addition to a description of the dases. Pyrimidine Metabolizing Enzymes: Kinases; Deamienzymes involved in the biosynthetic, degradative, and nases; Phosphorylase and Trans-Deoxyribosylase. Purine salvage pathways of nucleotides, the volume includes Metabolizing Enzymes: Kinases; Deaminases; Phosphorypurification methods and properties of pertinent enzymes. lases; Phosphoribosyltransferases; General Methods. Whenever possible, enzymes from eukaryotic as well as 1978, 640 pp., $44.50/£28.90 ISBN: 0-12-181951-5 prokaryotic sources are included.