Serum 25-Hydroxyvitamin D Levels in Pediatric Burn Patients
نویسندگان
چکیده
BACKGROUND Previous studies have implicated the important and active role of vitamin D in the immune system. OBJECTIVES The aim of this study was to evaluate serum levels of 25-hydroxyvitamin D in children with burn injuries. MATERIALS AND METHODS In this cross-sectional study, 118 patients with various degrees of burn injuries were enrolled. A checklist consisting of demographic data, total body surface area (TBSA) affected by burn, degree of burn, serum level of 25(OH)D, total protein, albumin, electrolytes, and parathyroid hormone was recorded for each patient. RESULTS Sixty-eight (57.6%) males and 50 (42.4%) females with a mean age of 4.04 years (SD = 3.04) were evaluated. The mean level of 25(OH)D was 14.58 ng/mL (SD = 6.94). Levels of 25(OH)D in four (3.39%) cases were higher than 30 ng/mL, while 95 (81.35%) cases had levels lower than 20 ng/mL, and 19 (16.10%) cases had levels of 21 - 30 ng/mL. The level of 25(OH)D was below recommended levels in 96.61% of cases, while 81.34% had vitamin D deficiency and 16.1% had insufficiency. We found a significant correlation between vitamin 25(OH)D and total protein, albumin, and total and ionized calcium (P < 0.001). There was also a significant negative correlation between 25(OH)D and TBSA affected by burn (P = 0.001). CONCLUSIONS The levels of 25(OH)D in children suffering from severe burns were low. Supplementation might be useful in patients with very low levels of serum vitamin D.
منابع مشابه
Low Serum Levels of 25-Hydroxyvitamin D in Association with Type 2 Diabetes in Indian Patients
Objective: Vitamin D deficiency is a common disorder worldwide and is indicated by low serum 25-hydroxyvitamin D levels. Recent studies have suggested an association of 25-hydroxyvitamin D deficiency with diabetes mellitus. The objective of this study is to investigate the relationship between 25-hydroxyvitamin D concentration and type 2 diabetes in South Indian patients. Materials and Methods...
متن کاملLow Serum 25‑hydroxyvitamin D levels: Predictive Value of Hematological and Inflammatory Markers in Patients with Urinary Tract Infection
Background: Low vitamin D has been linked to enhance inflammatory markers in various pathological conditions. We aimed to evaluate the urinary tract infection (UTI)-associated hematological and inflammatory markers mediated by low serum levels of 25-hydroxyvitamin D [25(OH)D]. Methods: Vitamin D level, hematological indices (Neutrophil-to-lymphocyte ratio [NLR], Monocyte-to-lymphocyte ratio [M...
متن کاملSerum 25-hydroxyvitamin D Levels in Patients Referred to Clinical Laboratories in Various Parts of Mashhad- Northeastern Iran
Introduction: Vitamin D has an important role in maintaining human health. The main source of vitamin D production is skin exposure to sunlight. Accordingly with the spread of apartment life culture, growth of industrial cities and the increase of air pollution; vitamin D deficiency and its implications is an important factor in the appearance of debilitating diseases in different age categorie...
متن کاملThe Relationship between Serum 25-hydroxyvitamin D Levels and Metabolic Syndrome in Birjand Children, East of Iran
Background: Metabolic syndrome (MS) is an important risk factor that is associated with vitamin D deficiency, according to recent studies. This study aimed to evaluate the relationship between serum 25-hydroxyvitamin D level and risk of metabolic syndrome in children in Birjand. Materials and Methods: A case-control study on 6 to 18 years old metabolic syndrome patients, this investigation was ...
متن کاملAssociation of 25-Hydroxyvitamin D Deficiency in Pediatric Epileptic Patients
OBJECTIVE Epilepsy is a chronic neurological disorder requiring long-term therapy using antiepileptic medications. Reports have incriminated long-term antiepileptic drugs use in deficiency of vitamin D and bone diseases in all age groups. We aimed to investigate the association between serum 25-hydroxyvitamin D levels and pediatric epilepsy in Indian patients. MATERIALS & METHODS We prospecti...
متن کامل