Effects of cholera toxin on cochlear endolymph production: model for endolymphatic hydrops.
نویسندگان
چکیده
To evaluate a possible role for adenylate cyclase [ATP pyrophosphate-lyase (cyclizing), EC 4.6.1.1] and adenosine 3':5'-cyclic monophosphate in the secretion of endolymph, we studied the effect of an intra-scala media injection of purified cholera toxin (an adenylate cyclase stimulant) on cochlear endolymph volume, endolymphatic potential, and endolymphatic Na and K concentrations.
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Two-phase endolymphatic hydrops: a new dynamic guinea pig model.
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ورودعنوان ژورنال:
- Proceedings of the National Academy of Sciences of the United States of America
دوره 73 5 شماره
صفحات -
تاریخ انتشار 1976