A bioinspired self assembled dimeric porphyrin pocket that binds electron accepting ligands.

نویسندگان

  • Karl Börjesson
  • Jakob G Woller
  • Elham Parsa
  • Jerker Mårtensson
  • Bo Albinsson
چکیده

A binding pocket consisting of two zinc porphyrins self assembled by Watson-Crick base pairing is presented. The porphyrin binding pocket is located in the confined environment of a lipid membrane whereas the DNA is located in the water phase. Bidentate electron accepting ligands are shown to coordinate in-between the two porphyrins.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Self-assembly of double-decker cages induced by coordination of perylene bisimide with a trimeric Zn porphyrin: study of the electron transfer dynamics between the two photoactive components.

We describe the thermodynamic characterization of the assembly process of a covalently connected trimeric Zn porphyrin induced by coordination to a bispyridyl functionalized perylene bisimide . The perylene bisimide ligands act as pillars via two axial coordination bonds with the porphyrinic Zn(ii) ions fixing the planes of the porphyrin units in a nearly co-facial orientation and inducing the ...

متن کامل

Probing flexibility in porphyrin-based molecular wires using double electron electron resonance.

A series of butadiyne-linked zinc porphyrin oligomers, with one, two, three, and four porphyrin units and lengths of up to 75 A, have been spin-labeled at both ends with stable nitroxide TEMPO radicals. The pulsed EPR technique of double electron electron resonance (DEER) was used to probe the distribution of intramolecular end-to-end distances, under a range of conditions. DEER measurements we...

متن کامل

Selective four electron reduction of O2 by an iron porphyrin electrocatalyst under fast and slow electron fluxes.

An iron porphyrin catalyst with four electron donor groups is reported. The porphyrin ligand bears a distal hydrogen bonding pocket which inverts the normal axial ligand binding selectivity exhibited by porphyrins bearing sterically crowded distal structures. This catalyst specifically reduces O(2) by four electrons under both fast and slow electron fluxes at pH 7.

متن کامل

Allosterically controlled threading of polymers through macrocyclic dimers.

As part of an ongoing study to construct a molecular Turing machine in which a polymer chain is encoded via allosteric information transfer between macrocyclic complexes, we describe the thermodynamic and kinetic characterization of a multicomponent self-assembled system based on a zinc porphyrin macrocyclic compound, a bidentate ligand (1,4-diazabicyclo[2.2.2]octane, DABCO), and a viologen-sub...

متن کامل

Self-complementary double-stranded porphyrin arrays assembled from an alternating pyridyl–porphyrin sequence

Oligomeric porphyrin arrays with an alternating pyridyl–porphyrin sequence were synthesized to explore double-strand formation through self-complementary pyridyl-to-zinc axial coordination bonds. Competitive titration experiments revealed the thermodynamic aspects involved in the zipper effect within double-strand formation. Multiple axial coordination bonds defined the stacked conformation, de...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Chemical communications

دوره 48 12  شماره 

صفحات  -

تاریخ انتشار 2012