Acute Haemolytic Anaemia.

Acute haemolytic anaemia associated with high titre cold agglutinins is an uncommon complication of primary atypical pneumonia. The first description of a case appears in a paper of Clough and Richter4 recording their observations on the haemagglutinins in a patient with bronchopneumonia. In the British literature Besterman and Brigden2 first reported a case and in surveying the literature found 25 previously published cases. Since then cases have been recorded by Neely et al.,'5 Sigenthaler,'6 Aaron' and by Stewart and Friedlander.'8 Dacie7' 9 has described the serological investigation of several cases. The condition is sufficiently rare to warrant reporting a further case with some observations on the serological findings.